Discuss the mechanisms by which type I interferons exert their antiviral effects
What will be an ideal response?
Type I interferons (IFN-\alpha and -\beta) block virus replication in infected cells and protect uninfected cells nearby from becoming infected. This is accomplished by: (1) inducing cellular genes that destroy viral RNA through endonuclease attack; and (2) inhibiting protein synthesis of viral mRNA by modifying the initiation factors required for protein synthesis. In addition, IFN-\alpha and -\beta activate natural killer (NK) cells. NK cells kill virus-infected cells by releasing cytotoxic granules through a mechanism that involves the engagement of activating and inhibitory receptors; if inhibitory signals predominate, the target cell is not killed; however, if activating signals predominate, the target cell is killed.
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Describe the controversy surrounding the barbiturate drug thiopental (Pentothal) and why this drug is no longer available
What will be an ideal response?
Behavioral and social approaches for physical activity promotion are complementary. _____________ approaches give people the skills to be physically active and overcome barriers to being active. ____________ approaches make it easier to use those skills.
Fill in the blank(s) with the appropriate word(s).
Which of the following terms means that the growth is enclosed in a sheath of tissue?
A) encapsulated B) carcinoma in situ C) remission D) oncogenic
When you are performing the Squat exercise you should exhale as you straighten your legs and hips to return to a standing position
Indicate whether the statement is true or false