After administering diphenoxylate to a client, the nurse would assess the client closely for increased CNS depression if the client was also receiving which medication? Select all that apply
A) Fexofenadine (Allegra)
B) Glyburide (DiaBeta)
C) Sucralfate (Carafate)
D) Zolpidem (Ambien)
E) Temazepam (Restoril)
Ans: A, D, E
Feedback:
The nurse should monitor a client closely for increased CNS depression when diphenoxylate (Lomotil) is given to a client taking antihistamines (fexofenadine), opioids, sedatives (zolpidem), and hypnotics (temazepam).
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