The nurse completes an assessment of a client who is prescribed filgrastim after a bone marrow transplant. The nurse would attend most closely to which parameters on the complete blood count?
1. Platelet count and reticulocyte count
2. Band count and reticulocyte count
3. Hemoglobin and hematocrit
4. Total white cell count and neutrophil count
Correct Answer: 4
Rationale 1: The platelet and reticulocyte counts do not increase.
Rationale 2: The reticulocyte count does not increase.
Rationale 3: Hemoglobin and hematocrit do not increase.
Rationale 4: Filgrastim mimics endogenous CSF and promotes an increase in the total WBC and in the percentage of neutrophils.
Global Rationale: Filgrastim mimics endogenous CSF and promotes an increase in the total WBC and in the percentage of neutrophils. The platelet, reticulocyte count, hemoglobin, and hematocrit do not increase.
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