Aldosterone antagonist drugs work to lower blood pressure by which mechanism of action?
1. Blocking the formation of renin in the RAAS pathway
2. Blocking receptors for aldosterone in the kidneys
3. Blocking receptors for aldosterone in the adrenal glands
4. Blocking the AT1 receptors in the RAAS pathway
Correct Answer: 2
Rationale 1: Aldosterone antagonists do not block the formation of renin.
Rationale 2: Aldosterone antagonists block aldosterone receptors in the kidneys, which lowers blood pressure.
Rationale 3: Aldosterone antagonists do not block the aldosterone receptors in the adrenal gland but in the kidney.
Rationale 4: Aldosterone antagonists do not block AT1 receptors.
Global Rationale: Aldosterone antagonists block aldosterone receptors in the kidneys, which lowers blood pressure. Aldosterone antagonists do not block the formation of renin; does not block the aldosterone receptors in the adrenal gland; do not block AT1 receptors.
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