Please place the steps in the correct order to assess your understanding of the clinical stages of tuberculosis infection and disease progression.

> Inhaled into lungs
> Exposure to TB droplets
> Lung macrophages engulf bacilli, infection occurs in 80-90% of cases
> Recurrent disease; tubercles break down; bacilli are released into lung cavities and circulation
> Primary TB disease with tubercles, symptoms occur in 5-10% of cases within 2 years
> Latency; bacilli go dormant in lungs; carrier state without symptoms may last for many years
> Disease spreads to extrapulmonary sites such as kidney, bones, brain with severe morbidity


> Exposure to TB droplets
> Inhaled into lungs
> Lung macrophages engulf bacilli, infection occurs in 80-90% of cases
> Primary TB disease with tubercles, symptoms occur in 5-10% of cases within 2 years
> Latency; bacilli go dormant in lungs; carrier state without symptoms may last for many years
> Recurrent disease; tubercles break down; bacilli are released into lung cavities and circulation
> Disease spreads to extrapulmonary sites such as kidney, bones, brain with severe morbidity

Biology & Microbiology

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