A woman who is pregnant with twins says, "There are lots of twins in my family, but most of them are not identical." How would the nurse respond?
1. "Usually when twins run in families they are identical twins."
2. "Some women have a genetic tendency to release two eggs each month."
3. "Identical twins are very rare."
4. "Many people think that twinning runs in families, but that has not been scientifically proven."
2
Rationale 1: Dizygotic twinning shows a familial pattern.
Rationale 2: Dizygotic (DZ) twinning shows a familial pattern, possibly because of the mother's genotype for ovulating two oocytes in a month.
Rationale 3: Monozygotic twinning occurs less frequently than dizygotic twinning but is not considered a rarity.
Rationale 4: The tendency to ovulate two oocytes in one month increases the potential for dizygotic twins. This tendency is thought to be genetic.
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