A client is seen in the clinic for migraine headaches. The nurse anticipates that which medication might be prescribed as a prophylaxis for migraines?
1. Propranolol (Inderal)
2. Acebutolol
3. Carvedilol (Coreg)
4. Metoprolol (Lopressor)
Correct Answer: 1
Rationale 1: Propranolol is a nonselective beta-adrenergic antagonist, blocking both beta1 and beta2 receptors all over the body; and so, is used in the prophylaxis of migraine headache.
Rationale 2: Acebutolol, a cardioselective beta1 antagonist similar to metoprolol, is used for HTN and recurrent ventricular dysrhythmia.
Rationale 3: Carvedilol is an alpha1 blocker as well as a beta receptor blocker that is not used for prophylaxis of migraine.
Rationale 4: Metoprolol is a selective beta1-adrenergic antagonist that is not used for migraines.
Global Rationale: Propranolol is a nonselective beta-adrenergic antagonist, blocking both beta1 and beta2 receptors all over the body; and so, is used in the prophylaxis of migraine headache. Acebutolol, a cardioselective beta1 antagonist similar to metoprolol, is used for HTN and recurrent ventricular dysrhythmia. Carvedilol is an alpha1 blocker as well as a beta receptor blocker that is not used for prophylaxis of migraine. Metoprolol is a selective beta1-adrenergic antagonist that is not used for migraines.
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