A patient with suspected Cushing syndrome is prescribed a 24-hour urine collection. What should the nurse explain to the patient about the reason for this urine collection?
1. It measures the amount of cortisol in the urine over 24 hours.
2. At least 2,000 mL of urine is required to perform the test.
3. It identifies urine specific gravity changes over a 24-hour period.
4. The 24-hour timeline reduces unwanted effects of medications excreted in the urine.
Correct Answer: 1
If the dexamethasone test is positive, a test for urinary free cortisol is made. This measures the amount of cortisol in the urine over 24 hours. The 24-hour urine collection is not performed because 2 L of urine is needed, to measure urine specific gravity, or to ensure medication excretion in the urine.
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