A client with bipolar disorder who had a relapse after discontinuing lithium has orders for
chlorpromazine (Thorazine) four times daily and twice-daily lithium.
The nurse's planning will be
aided if he understands that use of the phenothiazine will
a. bring hyperactivity under rapid control.
b. enhance the antimanic action of lithium.
c. minimize the side effects of lithium.
d. be used for long-term control of hyperactivity.
A
Manic symptoms are controlled by lithium only after a therapeutic serum level is attained. Because
this takes several days to accomplish, a drug with rapid onset is necessary to reduce the
hyperactivity initially. Options B and C: Phenothiazines neither enhance lithium's antimanic activity
nor minimize the side effects. Option D: Lithium will be used for long-term control.
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