A patient is taking drug X and receives a new prescription for drug Y, which is listed as an inducing agent. The nurse caring for this patient understands that this patient may require _____ doses of drug _____
a. lower; X
b. lower; Y
c. higher; X
d. higher; Y
ANS: C
An inducing agent stimulates the synthesis of CYP isozymes, which may increase the metabolism of other drugs as much as two- to threefold, thereby lowering the level of those drugs in the body and requiring higher doses to maintain drug effectiveness.
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