Which of the following events occurs first in the overall process of muscle stimulation?
A. Calcium ions bind to troponin.
B. Myosin heads bind to receptor sites on thin myofilaments.
C. Sodium and potassium channels open in the sarcolemma.
D. Calcium ions are released from the sarcoplasmic reticulum.
E. Acetylcholine is released into the synaptic cleft.
Answer: E
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