Hybridization methods are based on:
a. the ability of two nucleic acid strands that have complementary base sequences to bond specifically with each other and form a double-stranded molecule.
b. detecting phenotypic traits not detectable by conventional strategies.
c. the principles of complementary nucleic acid hybridization with those of nucleic acid replication that are repeatedly applied through numerous cycles.
d. determining the exact nucleotide sequence of a gene or gene fragment obtained from an organism.
A
The ability of complementary nucleic acid strands to bond specifically with each other and form a double-stranded molecule is what drives hybridization methods.
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