An individual whose resident normal microbiota overgrows the other indigenous organisms resulting in disease may be a result of:
a. the patient has received antibiotic treat-ment killing off some of the protective resident microbiota.
b. become immunocompromised or unable to fight off infection in normal conditions.
c. maybe suffering from a debilitating dis-ease resulting in a decreased balance be-tween normal microbiota and pathogenic organisms.
d. all of the scenarios are potentially asso-ciated with the development of disease.
D
All of these scenarios could lead to the imbalance in the resident normal microbiota of the human indigenous flora and result in the development of infection or disease. In addition to overgrowth by a particular organism due to successful antibiotic treatment and exposure to disease causing organisms, underlying diseases can also make a host more susceptible to infection by organisms that are normally kept under control by the nonspecific immune response.
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