A 6-month-old infant was born with a murmur. The pediatrician is recommending valve replacement/repair surgery based on which of the following lab values indicating intravascular hemolysis?
A) Increase in the number of red blood cells (polycythemia)
B) Excess of hemoglobin in the blood plasma (hemoglobinemia)
C) Elevated bilirubin levels
D) Decreased number of reticulocytes
Ans: B
Feedback:
Intravascular hemolysis is less common and occurs as a result of mechanical injury caused by defective cardiac valves, complement fixation in transfusion reactions, or exogenous toxic factors. Regardless of cause, intravascular hemolysis leads to hemoglobinemia, hemoglobinuria, and hemosiderinuria.
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