A public health nurse has cited a reduction in cancer risk among the many benefits of maintaining a healthy body mass index. Which of the following facts underlies the relationship between obesity and cancer?
A) Obesity can cause inflammation and hormonal changes that are associated with cancer.
B) Adipose tissue is more susceptible to malignancy than other types of connective tissue.
C) Increased cardiac workload and tissue hypoxia can interfere with normal cell differentiation.
D) Increased numbers of body cells increase the statistical chances of neoplastic cell changes.
Ans: A
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Obesity has a complex interplay with the development of cancer that is thought to result from the influence of hormonal changes and inflammation. It is not thought to be due to the increased number of cells in the body or to any particular susceptibility of adipose tissue. Increased cardiac workload and hypoxia are not known to cause neoplastic changes.
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