Very low concentrations of detergent make membranes leaky to small molecules and ions without damaging proteins. In isolated mitochondria exposed to detergent, the molecules of the electron transport chain and of ATP synthase remain intact
Do you expect ATP
synthesis to continue in the presence of low concentrations of detergent?
A. Yes, because all enzymes and electron
carriers are functional.
B. No, because with a leaky membrane, H+
gradient cannot be maintained.
C. No, because leaky membranes do not
allow NADH and FADH2 to donate their
electrons to the electron transport chain.
D. because leaky membranes inhibit
glycolysis.
B
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