Which statement explains the usefulness of the median toxicity dose best?
1. Is useful because drug amounts that are lower than the TD50 will not produce the desired effect.
2. Is useful for determining the efficacy and potency of a drug.
3. Is useful because it is not ethical to determine the LD50 in humans.
4. Is useful because drug amounts that exceed the TD50 will be lethal to half the population.
Correct Answer: 2
Rationale: Since the LD50 is not ethical to determine in humans, the TD50 is used. The LD50 is used to determine adverse effects in humans, not efficacy or potency.
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Which information should the nurse give to a child who is to have magnetic resonance imaging (MRI) of the brain?
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