A group of rats are bred in a laboratory to study muscle function. This group possesses a genetic defect that causes troponin to be incorrectly synthesized, making it non-functional. Because of this, the rats are entirely paralyzed. Which of the following correctly explains the impact of the defect on the muscle?

A. Troponin, when revealed by tropomyosin, won't be able to bind to the myosin heads of the thick filament.
B. Troponin won't pull away to reveal the actin binding spots of the thin filament after tropomyosin binds Ca+2.
C. Troponin, when revealed by actin, won't be able to bind to the myosin heads of the thick filament.
D. Troponin can't bind Ca+2, which stops tropomyosin from pulling away to reveal actin binding spots on the thin filament.


Answer: D

Anatomy & Physiology

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