Nonrandom chromosomal abnormalities are:
a. Congenital chromosome abnormalities that are consistently found in all tissues of an affected individual
b. Acquired chromosome abnormalities that are found in the abnormal or malignant tissue of an affected individual
c. Acquired chromosome abnormalities that are found in all tissues of an affected individual
d. Congenital chromosome abnormalities that are found in only one type of tissue of an affected individual
ANS: B
Cancer cytogenetics is a field that is built on the finding of nonrandom chromosome abnormalities in many types of cancer. Cytogenetic analysis of malignant cells can help determine the diagnosis and probable prognosis of a hematologic malignancy.
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