Drug A produces a certain therapeutic effect at a dose of 5 mg/kg. Drug B produces the same magnitude of effect at a dose of 0.1 mg/kg. How would the nurse describe the action of Drug A when compared to Drug B?
1. Drug A is more efficacious.
2. Drug A is less efficacious.
3. Drug A is more potent.
4. Drug A is less potent.
Correct Answer: 4
Rationale 1: Efficacy is a concept that refers to the magnitude of the maximal response to a drug.
Rationale 2: Efficacy is a concept that refers to the magnitude of the maximal response to a drug.
Rationale 3: It takes a higher dose of drug A to produce the same effect as drug B; therefore, drug A is less potent than drug B.
Rationale 4: It takes a higher dose of drug A to produce the same effect as drug B; therefore, drug A is less potent than drug B.
Global Rationale: It takes a higher dose of drug A to produce the same effect as drug B; therefore, drug A is less potent than drug B. Efficacy is a concept that refers to the magnitude of the maximal response to a drug.
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