he nurse is caring for a client diagnosed with systemic lupus erythematosus (SLE). What does the nurse understand about the etiology and pathogenesis of this condition? Select all that apply.
A) Clinical manifestations are mediated by antibody formation and the creation of immune complexes (IC).
B) Lupus is more common in men than in women.
C) Lupus can be drug-induced by the body's overreaction to medications such as isoniazid, hydralazine, and procainamide.
D) It is most common in individuals of Hispanic and Latino descent.
E) The rate ICs are cleared in the liver and spleen are believed to be impaired in SLE.
A) Clinical manifestations are mediated by antibody formation and the creation of immune complexes (IC).
C) Lupus can be drug-induced by the body's overreaction to medications such as isoniazid, hydralazine, and procainamide.
E) The rate ICs are cleared in the liver and spleen are believed to be impaired in SLE.
Explanation: A) Clinical manifestations of SLE are mediated by antibody formation and the creation of immune complexes (IC). The severity of the immune complexes depends on the characteristics of the antibody and the nature of the antigen. SLE is more common in women than in men, and is most common in individuals of African American and Asian descent.
B) SLE is more common in women than in men, and is most common in individuals of African American and Asian descent.
C) Lupus can be drug-induced by the body's overreaction to medications such as isoniazid, hydralazine, and procainamide.
D) SLE is more common in women than in men, and is most common in individuals of African American and Asian descent.
E) The rate at which ICs are cleared in the liver and spleen are believed to be impaired in SLE.
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