What liver function test is a sensitive indicator of injury to liver cells and useful in detecting acute liver disease such as hepatitis?
A) Clotting factors
B) SGGT
C) Serum aminotransferases
D) Alkaline phosphatase
C
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Antiviral drugs are indicated for the treatment of adults with chronic hepatitis B who have evidence of active viral replication and evidence of either persistent elevations in serum aminotransferases or histologically active disease. The drugs inhibit reverse transcriptase in the hepatitis B virus and cause DNA chain termination, leading to blocked viral replication and decreased viral load. Clotting factor alterations will be seen only in cases of severe liver damage. Serum gamma-glutamyl transferase and alkaline phosphatase may elevate with liver damage, but serum aminotransferases are the best indicator of hepatitis B
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