A client with liver disease displays alterations in coagulation. Which coagulation factors does the nurse understand may be impaired due to the client's liver dysfunction of clotting factor synthesis? Select all that apply.
A) I
B) II
C) VIII
D) VII
E) X
A) I
B) II
D) VII
E) X
Explanation: A) The liver is responsible for the synthesis of clotting factors I (prothrombin), II (fibrinogen), VII, IX, and X from amino acids. Factor VIII is not synthesized in the liver and is not directly impacted by the impairment of liver clotting factor synthesis.
B) The liver is responsible for the synthesis of clotting factors I (prothrombin), II (fibrinogen), VII, IX, and X from amino acids. Factor VIII is not synthesized in the liver and is not directly impacted by the impairment of liver clotting factor synthesis.
C) The liver is responsible for the synthesis of clotting factors I (prothrombin), II (fibrinogen), VII, IX, and X from amino acids. Factor VIII is not synthesized in the liver and is not directly impacted by the impairment of liver clotting factor synthesis.
D) The liver is responsible for the synthesis of clotting factors I (prothrombin), II (fibrinogen), VII, IX, and X from amino acids. Factor VIII is not synthesized in the liver and is not directly impacted by the impairment of liver clotting factor synthesis.
E) The liver is responsible for the synthesis of clotting factors I (prothrombin), II (fibrinogen), VII, IX, and X from amino acids. Factor VIII is not synthesized in the liver and is not directly impacted by the impairment of liver clotting factor synthesis.
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