A patient comes to the clinic with allergic rhinitis. Which of the following second-generation agents, administered nasally, would be most appropriate for this patient?
a. Azelastine (Astelin)
b. Chlorpheniramine (Chlor-Trimeton)
c. Desloratadine (Clarinex)
d. Phenindamine (Nolahist)
ANS: A
Azelastine blocks the release of histamine and is indicated for allergic or vasomotor rhinitis. It is administered by nasal spray and is a second-generation medication.
Chlorpheniramine is a first-generation agent and is administered by mouth.
Desloratadine is a second-generation medication administered only by mouth.
Phenindamine is also a first-generation medication taken by mouth.
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