The nurse is describing the mechanism of action of antimetabolites to a client with cancer. Which statement best describes how the antimetabolites kill cancer cells?
1. "They use the body's immune system to kill tumor cells."
2. "They disrupt metabolic pathways, slowing growth of cancer cells."
3. "They contain bacterial substances that can kill cancer cells."
4. "They change the shape of the DNA and prevent division of cancer cells."
Correct Answer: 2
Rationale 1: This describes biologic response modifiers.
Rationale 2: This describes antimetabolites.
Rationale 3: This describes antibiotic antineoplastics.
Rationale 4: This describes alkylating agents.
Global Rationale: Antimetabolites disrupt the critical cellular pathways of cancer cells which slows growth or kills the cell. Biologic response modifiers use the body's immune system to kill tumor cells. Antibiotic antineoplastics contain bacterial substances that can kill cancer cells. Alkylating agents change the shape of the DNA and prevent division of cancer cells.
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