To treat enuresis in a young girl, her pediatrician prescribes desmopressin, an antidiuretic hormone (ADH) nasal spray, before bedtime. What is the most likely rationale for this treatment?
A)
It removes water from the filtrate and returns it to the vascular compartment.
B)
It lessens the amount of fluid entering the glomerulus.
C)
It leads to the production of dilute urine.
D)
It causes tubular cells to lose their water permeability.
Ans:
A
Feedback:
ADH maintains extracellular volume by returning water to the vascular compartment. This leads to the production of concentrated urine by removing water from the tubular filtrate. In exerting its effect, ADH produces a marked increase in water permeability in tubular cells.
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