The nurse is notified that she is receiving a new patient and that the patient's old charts have been ordered to the floor

Question

When the old charts arrive, the nurse looks through them and notes the patient has a gene mutation that affects protein structure, producing hemoglobin S. The nurse knows that with this gene mutation, the patient will experiences symptoms of what?
A) Edema
B) Thrombotic organ damage
C) Metastasis of a glioblastoma
D) Amyotrophic lateral sclerosis

Answer 1

Ans: B

Feedback: Sickle cell anemia is an example of a genetic condition caused by a small gene mutation that affects protein structure, producing hemoglobin S. A person who inherits two copies of the hemoglobin S gene mutation has sickle cell anemia and experiences the symptoms of severe anemia and thrombotic organ damage resulting in hypoxia. Amyotrophic lateral sclerosis is a neurodegenerative disease that can occur as a result of an inherited mutation but not a mutation of hemoglobin S. The patient with sickle cell anemia may experience edema, but it would not be related to the gene mutation. A glioblastoma is a neurologic tumor.