Which neurotransmitter is decreased in delirium causing agitation, confusion, and hallucinations?
a. dopamine c. glutamate
b. norepinephrine d. acetylcholine (Ach)
D
The neurotransmitter hypothesis states that the increased metabolic demands on the brain result in poor oxygenation of the brain, thus leading to a decrease in acetylcholine (Ach), a major neurotransmitter needed for attention and cognition. When Ach is decreased, the result is increased levels of other more activating neurotransmitters, such as dopamine, norepinephrine, and glutamate. When these increase, it leads to the agitation, confusion and hallucinations seen in the client with delirium.
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ANS:
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