An ulcer caused by H. pylori can be successfully treated with which classification of drugs?
1. Antacids
2. Proton-pump inhibitors
3. H2-receptor blockers
4. Antibiotics
4
Rationale 1: Antacids neutralize the stomach acid.
Rationale 2: Proton-pump inhibitors reduce acid secretion in the stomach.
Rationale 3: H2-receptor blockers suppress the volume and acidity of stomach acid.
Rationale 4:H. pylori is associated with 80% of all duodenal ulcers and 70% of all gastric ulcers. The microorganism is well adapted to neutralize the high acidity in the gastric environment. These infections can remain active for life if not treated appropriately. Eliminating the organism causes ulcers to heal more rapidly and to remain in remission longer.
Global Rationale: H. pylori is associated with 80% of all duodenal ulcers and 70% of all gastric ulcers. The microorganism is well adapted to neutralize the high acidity in the gastric environment. These infections can remain active for life if not treated appropriately. Antibiotics treat the infection by eliminating the organism,which causes ulcers to heal more rapidly and to remain in remission longer. Antacids neutralize the stomach acid. Proton-pump inhibitors reduce acid secretion in the stomach. H2-receptor blockers suppress the volume and acidity of stomach acid.
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