Which causative factor(s) may be responsible for primary endocrine disorders? (select all that apply.)
a. Hormone overproduction
b. Long periods of limited mobility
c. Trauma
d. Severe infection
e. Effects of certain drugs
A, D
Endocrine disorders are caused by an imbalance in the production of hormone or by an alteration in the body's ability to use the hormones produced. Primary endocrine dysfunction means that an endocrine gland is either oversecreting or undersecreting hormone(s). Tumor or hyperplasia of the endocrine gland may lead to hypersecretion. Infection, mechanical damage, or an autoimmune response may be an inflammatory response in a gland and lead to hyposecretion. Secondary endocrine dysfunction occurs from factors outside the gland itself. Medications, trauma, hormone therapy, and other factors may cause secondary dysfunction. Long periods of limited mobility do not cause endocrine disorders.
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