Mr. Quitman is 70 years old, weighs 132 lb, and is 5 ft 9 in. tall. At his follow-up appointment after several tests, his physician told him that he has bladder cancer and referred him to an oncologist. The oncologist explained that the treatment regimen will include an IV injection of doxorubicin for 3 consecutive days every 3 to 4 weeks. The oncologist ordered doxorubicin 45 mg by IV injection for the first three daily doses. On hand are 10 mL single-use vials of doxorubicin
. According to the package insert, the usual dose is 60-90 mg/m2 IV injection every 21 days, 20-30 mg/m2/day IV for 3 consecutive days every 3 to 4 weeks, or 20 mg/m2 IV weekly, for
a total cumulative dose of 550 mg/m2. Determine whether this is a safe dose for this patient. If the dose is safe, calculate the amount to administer: ________. If the dose is not safe, write: not safe.
Fill in the blank(s) with the appropriate word(s).
27 mL
Calculate Mr. Quitman's BSA:
BSA = 1.706 m2
Determine whether the dose is safe:
The maximum dose for the regimen described by the oncologist is 30 mg/ m2/day.
1.706 m2 × 30 mg/m2 = 51.18 mg
The ordered dose is less than 51.18 mg, so the dose is safe.
Calculate the amount to administer:
H = 50 mg; Q = 30 mL; D = 45 mg
A = 0.9 × 30 mL
A = 27 mL
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