Cholesterol, triglycerides, and phospholipids travel between the liver and peripheral tissues through which mechanism?
1. Bound to apoproteins
2. As unbound free molecules
3. Bound to albumin
4. Bound separately in molecule complexes
Correct Answer: 1
Rationale 1: Apoproteins are specific for cholesterol, triglycerides, and phospholipids, and they act as carrier molecules for transporting these lipids through the blood.
Rationale 2: Lipid molecules are not soluble in plasma and so require protein binding for transport.
Rationale 3: Albumin is the most common plasma protein, but it is not specific as a carrier for cholesterol, triglycerides, and phospholipids.
Rationale 4: Lipoprotein molecules that combine lipids with a carrier protein contain different amounts of cholesterol, triglycerides, and phospholipids.
Global Rationale: Apoproteins are specific for cholesterol, triglycerides, and phospholipids, and they act as carrier molecules for transporting these lipids through the blood. Lipid molecules are not soluble in plasma and so require protein binding for transport. Albumin is the most common plasma protein, but it is not specific as a carrier for cholesterol, triglycerides, and phospholipids. Lipoprotein molecules that combine lipids with a carrier protein contain different amounts of cholesterol, triglycerides, and phospholipids.
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