The protozoan that causes malaria is an intracellular parasite of red blood cells (RBCs). An adaptive immune response to this parasite is problematic because
A. red blood cells do not produce MHC and, therefore, do not display the fact that they have been infected by presenting antigen.
B. the parasite damages leukocytes along with RBCs.
C. RBCs normally produce cytokines necessary for adaptive immune response, which this infection prevents.
D. complement cannot effectively destroy RBCs.
E. RBCs never enter lymphoid tissue.
Answer: A
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