Some mutagens cause genetic changes that can be "corrected" by reexposing cells to the same mutagen. Other mutagens do not behave in this way. Provide one example of each of these two types of agents and describe the mutational changes caused in DNA

Explain why some mutagens behave in one way, whereas others do not.

What will be an ideal response?


Mutagens that cause base substitutions are "corrected" by mutagens of the same class (nitrous acid, 2-aminopurine, and 5-bromouracil). Frameshift mutations are "corrected" by the same class of frameshift mutagens, but not by mutagens that cause base substitutions. X-rays cause major structural changes in chromosomes (deletions, translocations, etc.) and are not "corrected" by any mutagen, including X-rays.

Biology & Microbiology

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