The nurse is caring for an Asian American client diagnosed with terminal cancer. Which factor should the nurse consider to achieve adequate pain control for the client?
1. All ethnic groups respond to medications in the same manner.
2. The only variation in drug metabolism occurs among African Americans.
3. Asians respond differently to antidepressants only.
4. Opioids are metabolized differently in individuals of Asian and Native American descent.
Correct Answer: 4
Rationale 1: Research demonstrates a biologic basis for variations or differences in metabolism response to agents among various ethnic groups.
Rationale 2: Drugs are metabolized differently by various ethnic groups.
Rationale 3: Asians respond differently to antidepressants, antidysrhythmics, and opioids.
Rationale 4: Opioids are also metabolized differently by clients of Asian descent. The nurse must understand how the drug is metabolized to ensure that the correct dose is being given.
Global Rationale: Opioids are also metabolized differently by clients of Asian descent. The nurse must understand how the drug is metabolized to ensure that the correct dose is being given. Research demonstrates a biologic basis for variations or differences in metabolism response to agents among various ethnic groups. Drugs are metabolized differently by various ethnic groups. Asians respond differently to antidepressants, antidysrhythmics, and opioids.
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