Explain why individuals with cystic fibrosis have different levels of severity of the disease. What will be an ideal response?
ANSWER: Both the types and the numbers of mutations in the single gene responsible for cystic fibrosis,
called the CFTR gene, can produce different disease phenotype. More than 1,900 mutations
of several types have been identified in this gene. People with cystic fibrosis have a wide
range of clinical symptoms. The relationship between the type and location of the CFTR
mutation and the clinical phenotype has been investigated for a number of mutant alleles.
Some mutations totally disrupt protein synthesis and severe clinical symptoms result. In other
mutations, proteins may be synthesized but only partially functional. These types of
mutations are associated with milder forms of the disease. It is possible for someone with
cystic fibrosis to carry two different mutant alleles and be a compound heterozygote. This
genetic variability further contributes to the range of phenotypes seen in cystic fibrosis
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The pathogenic state involving the disruption and destruction of tissues by microbes is referred to as a(n) ______ disease
Fill in the blank(s) with the appropriate word(s).
If a nail is pounded into the trunk of a tree, what plant structure would it encounter first?
A) phloem B) xylem C) cork D) cork cambium
Infants born blind will not smile or frown because they have never seen anyone exhibit these expressions.
Answer the following statement true (T) or false (F)
The scientist(s) who used an enzyme to destroy proteins to show that protein was not the genetic information transferred by bacteria was/were
A. Avery and Macleod. B. Watson and Crick. C. Griffith. D. Hershey and Chase. E. Wilkins and Franklin.