A nurse is discussing the use of benzodiazepines as sedative-hypnotic agents with a group of nursing students. A student asks about the actions of these drugs in the central nervous system. The nurse makes which correct statement?

a. "Benzodiazepines affect the hippocampus and the cerebral cortex to cause antero-grade amnesia."
b. "Benzodiazepines depress neuronal func-tions by acting at a single site in the brain."
c. "Benzodiazepines induce muscle relaxa-tion by acting on sites outside the central nervous system."
d. "Benzodiazepines promote sleep through effects on the limbic system."


A
All beneficial and most adverse effects of benzodiazepines occur from depressant actions in the central nervous system (CNS); the various effects depend on the site of action. Anterograde am-nesia is the result of effects in the hippocampus and the cerebral cortex. Benzodiazepines act at multiple sites in the CNS. Muscle relaxant effects are the result of actions on supraspinal motor areas in the CNS. Benzodiazepines promote sleep through effects on cortical areas and on the sleep-wakefulness "clock."

Nursing

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