Cynthia is taking valproate (Depakote) for seizures and would like to get pregnant. What advice would you give her?
1. Valproate is safe during all trimesters of pregnancy.
2. She can get pregnant while taking valproate, but she should take adequate folic acid.
3. Valproate is not safe at any time during pregnancy.
4. Valproate is a known teratogen, but may be taken after the first trimester if necessary.
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