Which of the following are the main therapeutic interventions for Kawasaki disease in the first 10 days of the disease?
a. antibiotics and Tylenol
b. blood transfusions and a cortisone product
c. diuretics and administration of packed cells
d. intravenous immune globulin and aspirin
D
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A Incorrect. The etiology of KD remains unconfirmed; therefore, antibiotics are not the mainstay of therapy in the first 10 days. Tylenol is an antipyretic and analgesic medication but has no anti-inflammatory effects.
B Incorrect. Blood transfusions and a cortisone product are not the mainstay of therapy for KD in the first 10 days. Methylprednisolone has been used in select clients who are refractory to multiple doses of IVIG in combination with aspirin.
C Incorrect. Diuretics and administration of packed cells are not the mainstay of therapy for KD in the first 10 days.
D Correct. Intravenous immune globulin (IVIG) and aspirin are the main therapeutic interventions for KD in the first 10 days of the disease. IVIG usually results in rapid resolution of congestive heart failure, defervescence of fever, and normalization of sedimentation rate. IVIG reduces the incidence of coronary artery aneurysms. Aspirin is given to control the high remittent fever (101-105 F) and for inflammation.
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