Which statement about the effects of isotretinoin is true?
A. Exposure to isotretinoin during the third trimester results in severe abnormalities, but exposure during the first trimester is not linked to adverse effects.
B. Exposure to isotretinoin during the first trimester results in only minor abnormalities, but exposure during the third trimester is linked to severe abnormalities.
C. Exposure to isotretinoin during the first trimester results in eye, ear, brain, heart, and immune system abnormalities.
D. While exposure to isotretinoin can results in severe birth defects, risk to the developing organism is reduced if the mother receives large doses of vitamin A.
Answer: C
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