A patient will receive intrathecal liposomal cytarabine (DepoCyt) to treat acute myelogenous leukemia. The provider has ordered the concurrent administration of dexamethasone. The nurse understands that this is given to:
a. prevent bone marrow suppression.
b. prevent hair loss and stomatitis.
c. reduce the incidence of pulmonary edema.
d. reduce the severity of chemical arachnoiditis.
ANS: D
Chemical arachnoiditis can occur with the liposomal formulation of cytarabine; dexamethasone is given to reduce the incidence and severity of this side effect. It is not used to prevent bone marrow suppression. It is not given to minimize hair loss or stomatitis. It does not reduce the incidence of pulmonary edema.
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