Which of the following is true of the topoisomerases found in bacteria?

A. Type I topoisomerases introduce single-stranded breaks and as a result change the linking number by 1.
B. Type I topoisomerases introduce single-stranded breaks and as a result change the linking number by 2.
C. Type II topoisomerases introduce single-stranded breaks and as a result change the linking number by 2.
D. Type II topoisomerases introduce double-stranded breaks and as a result change the linking number by 1.
E. Type I topoisomerases are the only category that can introduce negative supercoils.


A

Biology & Microbiology

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