The following disorder commonly presents with vesicular or ulcerated lesions with a yellow base on the oral mucosa and lips
A. Aphthous ulcer
B. Herpes simplex I
C. Coxsackie viral infection
D. All of the above
ANS: A
Aphthous ulcers are painful and usually small (less than 1 cm). The ulcer is shallow, surrounded by erythema and mild edema. The base of the ulcer is pale yellow or gray. Orolabial ulcers are often caused by herpes simplex type 1 virus. The ulcers are typically preceded by a prodromal phase of tenderness, followed by edema at the site where an individual or cluster of vesicles forms and progresses to ulceration. The prodromal phase may also include fever. Hand-foot-and-mouth disease is caused by a coxsackievirus. Painful skin and oral lesions are often preceded by a period of malaise and fever. The patient often presents once the lesions appear on the lips and/or oral mucosa. The lesions erupt as vesicles, which later ulcerate.
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