After asking the family to describe M.E.'s behavior, you determine that she is in stage 2 of

Alzheimer's three stages. Describe common signs and symptoms for each stage of the disease.

What will be an ideal response?


• Stage 1: Early (mild): First symptoms up to 4 years
Early AD is marked by mild cognitive decline. Friends, family members, or co-workers begin to
notice problems with memory and judgment, as well as subtle personality changes. There might
be performance issues in work or social settings, and one might seem subdued and withdrawn in
social or mentally challenging situations. One might misplace valuable objects or have difficulty
planning, organizing, or concentrating. One might have the inability to perform complex tasks such
as managing finances or grocery shopping, and exhibit knowledge deficits about personal history.
These changes might be measurable during clinical testing or discernible during a detailed medical
interview.
• Stage 2: Middle (moderate): 2 to 3 years
Moderate AD is marked by major gaps in memory and cognitive deficits. One retains information
about self and names of spouse and children but is disoriented to place and time (day, week,
and season). Speech and language deficits are more obvious; one might be less talkative, have
decreased use of vocabulary, be increasingly nonfluent, and eventually aphasic. One requires help
with activities of daily living (ADLs) and experiences bowel and bladder incontinence. One might
experience paranoia, agitation, and insomnia, often having auditory and visual hallucinations that
result in behavioral problems. One tends to wander and become lost.
• Stage 3: Late (severe)
Severe AD, the final stage, is when an individual loses the ability to respond to his or her
environment and speak. One might still respond to his or her own name but lose facial recognition,
even of familiar faces. One requires help with eating and ambulating. Eventually, one loses the ability
to sit without support, smile, and hold up the head. Ultimately, one's reflexes become abnormal,
muscles grow rigid, and swallowing is impaired.

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