A female patient who is not taking any other medications is prescribed aliskiren (Tekturna), a direct renin inhibitor (DRI). The nurse reviews medication information with the patient
Which statement by the patient indicates understanding of the teaching?
a. "If I get pregnant, I should stop taking this drug by the second trimester."
b. "If I take this drug with a high-fat meal, it will be more effective."
c. "I should restrict my potassium intake while taking this drug."
d. "I should take this medication 1 hour before sitting down to a meal."
ANS: D
DRIs should be taken on an empty stomach to improve their bioavailability. Patients should not take this drug when pregnant and should stop immediately upon finding out they are pregnant. Dosing with a high-fat meal reduces the drug's bioavailability. DRIs rarely cause hyperkalemia when taken alone.
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