Following a lecture on hemostasis, a nursing student accidently cuts her hand while preparing supper for her family. She watches the laceration very closely. Sure enough, the first thing she notes is:
A) Small hair-like strands form a blood (fibrin) clot.
B) Limited bleeding initially as a response to the small vessel walls being sealed by a platelet plug.
C) Clot retraction by pushing serum out of the clot and joining the edges of the broken vessel.
D) Initially, it takes a few seconds for blood to appear as a result of vessel spasm.
Ans: D
Feedback:
There are five stages in hemostasis, with the first step being transient vessel vasospasm. Vessel spasm is initiated by endothelial injury and caused by local and humoral mechanisms. It is a transient event, usually lasting less than 1 minute. For smaller vessels, release of the vasoconstrictor TXA2 is responsible for much of the vessel spasm. Formation of the platelet plug, development of an insoluble fibrin clot, and clot retraction happen after vessel spasm.
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