Which one of the following statements about Pax6 and eye development is incorrect?
A. Binding of Pax6 protein to the cisregulatory
elements of its target genes results
in activation of some genes and repression of
others.
B. The specific program of eye development
for a given species depends on the genes
downstream of Pax6 in that species' genome.
C. In the fruit fly, the total number of genes
downstream of Pax6 that are needed for eye
development is approximately 2000.
D. Some of the genes influenced by Pax6
protein are activated or repressed indirectly
by other transcription factors "turned on" by
Pax6.
E. The downstream target genes for Pax6
protein in different organisms are all very
similar.
E
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