A patient is being treated for a systemic fungal infection with amphotericin B (Abelcet) and will be discharged home from the hospital to complete every other day infusions of the medication for 6 to 8 weeks
The nurse provides discharge teaching before dismissal. Which statement by the patient indicates a need for further teaching?
a. "I may experience headaches and pain in my lower back, legs, and abdomen."
b. "I may need to take potassium supplements while taking this drug."
c. "I should take acetaminophen and diphenhydramine before each infusion."
d. "I will need to have blood drawn for serum creatinine and BUN levels every 3 to 4 days."
ANS: A
Headaches, lower back pain, leg pain, and abdominal pain occur with intrathecal administration of amphotericin B. Patients taking amphotericin may experience hypokalemia and may need potassium supplements. Acetaminophen and diphenhydramine should be taken to minimize infusion reaction effects. Renal function should be monitored every 3 to 4 days during treatment.
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