The nurse is preparing to administer medication to a patient receiving cyclophosphamide (Cytoxan). To protect against the side effect of hemorrhagic cystitis, the nurse would expect to administer
a. Decadron.
b. diphenhydramine (Benadryl).
c. mesna (Mesnex).
d. leucovorin.
ANS: C
Cyclophosphamide can cause acute hemorrhagic cystitis; to prevent this, the nurse should expect to administer mesna, which is a protective agent.
Decadron, diphenhydramine, and leucovorin are indicated for prevention of side effects associated with different anticancer agents.
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