Describe the events that occur at a skeletal neuromuscular junction. Include the following in your answer : action potential (on axon and muscle fiber), end-plate potential, terminal button, ACh, Ca+2 channels, motor end plate, depolarization, and Na+ channels

What will be an ideal response?


When an action potential reaches the terminal button on the axon, voltage-gated Ca2+ channels open, allowing Ca2+ ions to enter the button. This causes the release of ACh, which binds to Na+ channels on the muscle cell's membrane (called the motor end plate). These channels open and allow Na+ ions to enter the muscle cell, causing depolarization; this is called the end-plate potential. This depolarization causes nearby voltage-gated Na+ channels to open and initiate action potentials on the muscle cell.

Anatomy & Physiology

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Anatomy & Physiology